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Thus, mouse primary neurones may be useful as models for WNV infection in vitro. While WNV causes fatal encephalitis in most laboratory strains mice following peripheral inoculation, recently trapped wild mice such as MBT new balance 574 pas cher strains are completely resistant.6 The growth of WNV in susceptible BALB/c mouse neurones was compared with that in neurones from resistant MBT mice (Figure 3). No difference was observed in the yields of WNV between the both cultured primary neurones at 24 h postinfection.
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