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A Western blot analysis revealed that the expression of h l(3)mbt I and h l(3)mbt II proteins was induced in the U251/h l(3)mbt I and U251/h l(3)mbt II cells, respectively, at 48 h after the medium change (Figure 5a). When h l(3)mbt I ugg pas cher femme and h l(3)mbt II were induced for more than 48 h, a significantly higher prevalence of cells failed to complete normal mitosis and became multinucleated (Figure 5b). In contrast, AxCANCre treated U251/mock cells completed mitosis and exhibited normal nuclear morphologies.
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