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Top of pageResultsThe 3xMBT region of L3MBTL1 is sufficient for its chromatin association in vivo and in vitroTo test whether L3MBTL1 is chromatin associated in vivo, we isolated nuclei from K562 erythroleukemia cells that express appreciable levels of L3MBTL1 (MacGrogan et al., 2004), and mulberry outlet generated soluble (nucleoplasm) and insoluble (chromatin) fractions, as described (Mendez and Stillman, 2000). L3MBTL1 protein is found in the chromatin fraction (residual chromatin pellet; lane ...
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