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Recent genetic studies have demonstrated that several PcG like chromatin binding factors identified in Drosophila are essential not only for gene silencing but also for the structural changes of the chromosome during mitosis. For example, HP1 (heterochromatin protein 1), which carries a motif called chromo domain that is also present in Pc protein, is a structural component of heterochromatin and is necessary for chromosome condensation and segregation (Kellum et al., 1995; Pak et al., 1997). CCF ...
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