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PAC clone dJ1118N11 spanned the der(1)t(1;20)(p32;q12) breakpoint (see Figure 4c), whereas PAC clone dJ440H8 spanned the der(13)t(13;20)x4 and the mar1 breakpoints.In MONO MAC 1 cells, a cell line with a hyperdiploid modal chromosome number, several unbalanced rearrangements cheap michael kors were seen, with deletion of the proximal portion of the CDR (Figure 4d). YAC clones 808C5 and 804C12 showed only one signal on chromosome 20, whereas all YACs telomeric to 936E4 showed two signals, one at the chromosome 20 and one on a der(4)t(4;20)(q35;q12). Allelic loss was found throughout the length replica michael kors handbags of chromosome arm 20q (see Figure 1), suggesting the der(4)t(4;20)(q35;q12) occurred after chromosomal loss and duplication.Three cell lines (HEL, MEG O1, MOLM 1) showed complete loss of the CDR.
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